Zymetech employs a team of scientists with a strong educational background in biochemistry, medical sciences, microbiology, food science, and pharmacy. Zymetech’s main research emphasis is on how cod trypsins act against upper respiratory virus infections like the common cold, as well as against bacterial infections and in wound healing applications.
Zymetech relocated to a new facility in Reykjavik in 2014 where the company established a state of the art research laboratory and a clean room for the purification of enzymes.

Product Development

The first products from Zymetech were in the PENZIM® derma health line, introduced in 1999. The PENZIM® Gel and PENZIM® Lotion have established incredibly loyal customer base in Iceland. Zymetech has further developed enzyme based health and cosmetic formulations that are sold under the various private labels of our partners.

In 2010 Zymetech partnered with Enzymatica AB in Sweden to develop a product acting against the common cold. This led to the development of the mouth spray ColdZyme® that came on the market in Sweden in 2012 and is now sold all over Scandinavia and elsewhere in Europe. ColdZyme® is the first CE marked Medical Device of the company.

At the beginning of 2015 Zymetech launched ColdZyme® under the brand name PreCold® in Iceland with great success.

In 2015 Zymetech received the Icelandic Innovation Award for its achievements in research and development.

Research Focus

Scientific Advisors

Our scientific advisors are well known in the field of enzyme research, respiratory infections and clinical research.

Ágústa Guðmundsdóttir

Dr. Ágústa Guðmundsdóttir is the R&D Director at Zymetech and professor emeritus at the School of Health Sciences, University of Iceland (UI). She is one of the founders of Zymetech and serving as a…

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Stefán Jökull Sveinsson

Stefán currently works as an independent consultant for various pharmaceutical and life science companies as well as for private equity companies. He has over 23 years of experience in the…

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Charles S. Craik

Dr. Charles S. Craik currently serves as Professor of Pharmaceutical Chemistry and Director of Chemistry and Chemical Biology Graduate Group at UCSF. He received his education and training at…

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Sigurður Guðmundsson

Sigurður Guðmundsson is a Professor of Internal Medicine at the University of Iceland. Graduated from the University of Iceland Medical School in 1975, postgraduate training in Iceland until 1978 and…

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Researchers at Zymetech have published numerous articles on enzyme technology.

  • Gudmundsdóttir, Ágústa, Hilmar Hilmarsson, and Bjarki Stefansson. “Potential Use of Atlantic Cod Trypsin in Biomedicine.” BioMed research international 2013 (2013).

  • Ásgeirsson, Bjarni, Jay W. FOX, and Jón B. BJARNASON. “Purification and characterization of trypsin from the poikilotherm Gadus morhua.” European journal of biochemistry 180.1 (1989): 85-94.

  • Jónsdóttir, Gudrún, Jón Bragi Bjarnason, and Ágústa Gudmundsdóttir. “Recombinant cold-adapted trypsin I from Atlantic cod—expression, purification, and identification.” Protein expression and purification 33.1 (2004): 110-122.

  • Stefansson, Bjarki, et al. “Characterization of cold-adapted Atlantic cod (Gadus morhua) trypsin I—Kinetic parameters, autolysis and thermal stability.” Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 155.2 (2010): 186-194.

  • Ásgeirsson, Bjarni, and Jón Bragi Bjarnason. “Structural and kinetic properties of chymotrypsin from Atlantic cod (Gadus morhua). Comparison with bovine chymotrypsin.” Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 99.2 (1991): 327-335.

  • Guðmundsdóttir, A., and J. Bjarnason. “Applications of cold-adapted proteases in the food industry.” Novel enzyme technology for food applications (2007): 205.

  • Kristjánsson, Magnús M., Bjarni Ásgeirsson, and Jón B. Bjarnason. Serine proteinases from cold-adapted organisms. Springer US, 1997.

  • Asgeirsson, Bjarni, Einar Mäntylä, and Jón Bragi Bjarnason. “Isolation, Characterization and Utilization of Psychrophilic Proteinases from Atlantic Cod.” Bioorganic Chemistry in Healthcare and Technology. Springer US, 1991. 299-302.

  • Stefansson, B., G. B. Sandholt, and A. Gudmundsdottir. 2017. ‘Elucidation of different cold-adapted Atlantic cod (Gadus morhua) trypsin X isoenzymes’, Biochim Biophys Acta, 1865: 11-19.